Showing posts with label microbiome. Show all posts
Showing posts with label microbiome. Show all posts

Thursday, November 9, 2017

How The Microbiome Destroyed The Ego, Vaccine Policy, And Patriarchy

How The Microbiome Destroyed The Ego, Vaccine Policy, And Patriarchy | microbiome_revolutionary_implications1 | General Health Medical & Health Science & Technology Special Interests Vaccines


The relatively recent discovery of the microbiome is not only completely redefining what it means to be human, to have a body, to live on this earth, but is overturning belief systems and institutions that have enjoyed global penetrance for centuries.


A paradigm shift has occurred, so immense in implication, that the entire frame of reference for our species’ self-definition, as well as how we relate fundamentally to concepts like “germs,” have been transformed beyond recognition. This shift is underway and yet, despite popular interest in our gut ecology, the true implications remain unacknowledged.


It started with the discovery of the microbiome, a deceptively diminutive term, referring to an unfathomably complex array of microscopic microorganisms together weighing only 3-4 lbs. in the average human, represents a Copernican revolution when it comes to forming the new center, genetically and epigenetically, of what it means in biological terms to be human.


Considering the sheer density of genetic information contained within these commensals, as well as their immense contribution towards sustaining basic functions like digestion, immunity, and brain function, the “microbiome” could just as well be relabeled the “macrobiome”; that is, if we are focusing on the size of its importance rather than physical dimensionality.


For instance, if you take away the trillions of viruses, bacteria and fungi that coexist with our human cells (the so-called holobiont), only 1% of the genetic material that keeps us ticking, and has for hundreds of millions of years, remains. One percent isn’t that much for the ego to work with, especially considering it now has to thank what were formerly believed to be mostly “infectious agents” for the fact that it exists. Even more perplexing, the remaining 1% of our contributed DNA to the collective gene pool of the holobiont is at least 8% retroviral (yes, the same category as HIV) in origin!


Us Against Them?


Once the object of modern medicine’s fundamental responsibility – the human body – is redefined and/or perceived with greater veracity, and “germs” become less other and more self, a challenge for germ theory which seeks to differentiate between the “good” germs we are versus the “bad” ones out there that we must fight with antibiotics and vaccines.


As many readers are already poignantly aware, today’s political climate and agenda is unilaterally pro-vaccination on both sides of the aisle (conveniently funded by the same industry lobbyists), with a tidal wave of bills across the U.S. set to eliminate exemptions against mandatory vaccination. The rationale, of course, is that deadly germs can only be prevented from killing the presumably germ-free host through injecting dead, weakened or genetically modified germ components to “prevent” theoretical future exposures and infection. This concept is of course intellectually infantile, and if you do some investigating you’ll find it was never quite grounded in compelling evidence or science.


But the intellectual implications of the microbiome go even deeper than undermining germ theory, vaccine policy, and the culture of medical monotheism that upholds these constructs…


Maternal Origins of Health and Ultimately our Species Identity


Deep within the substratum of humanity’s largely unquestioned assumptions of what it means to be human, the microbiome has also fundamentally displaced a latent patriarchal prejudice concerning the relative importance and contribution of the man and woman towards the health and ultimately the continuation of our species.


It has been known for some time that only women pass down mitochondrial DNA, already tipping the scales in favor of her dominant position in contributing genetic information (the seat of our humanity or species identity, no?) to offspring. The microbiome, however, changes everything in favor of amplifying this asymmetry of hereditary influence. Since we are all designed to gestate in the womb and come through the birth canal, and since the neonate’s microbiome is therein derived and established thereof, it follows that most of our genetic information as holobionts is maternal in origin. Even when the original colonization eventually changes and is displaced through environmentally-acquired microbial strains as the infant, child, adolescent, and then adult, develops, the original terrain and subsequent trajectory of changes was established through the mother (unless of course we were C-sectioned into the world).


Put in simpler terms: if 99% of what it means to be human is microbiome-based, and if the mother contributes most, if not all, of the original starting material, or at least the baseline and trajectory of future changes in the inner terrain, then her contribution becomes vastly more important than that of the father.


Moreover, the conditions surrounding gestation (important because of maternal-to-fetal microbiome trafficking in utero), her general health, and the way in which she gives birth (home, birth center, or hospital) now take on vastly greater importance than previously imagined. In other words, being born in a hospital via C-section and vaccination, will produce, genetically and epigenetically, a human that is so different – qualitatively – from one born at home, naturally, that they could almost be classified as different species, despite sharing nearly identical eukaryotic DNA (remember, only 1% of the holobiont’s total).


Given this perspective, obstetric interventions are the archetypal expression of a male-dominated paradigm that seeks to manage a woman’s birth experience with largely unacknowledged consequences for the health of our species. Protecting health and preventing disease has now been traced back to the origins of the microbiome, best expressed through natural birth in the home, which has been estimated to be as much as 1,000 times safer than a hospital birth despite propaganda to the contrary.


In light of the new, microbiome-based view, the male role in protecting the health of women and children will be irrevocably downgraded in importance, not just professionally and medically, but biologically.  First, it is interesting to look at the ancient roots of the biology-based psychospiritual disparities that exist between men and women, and which still influence today’s practice of medicine.


It would appear that men have from the beginning of time envied the creative role of women in conception, pregnancy, birth and caretaking. Erich Fromm also described the pyschospiritual implications for men of this biologically-based existential disparity in terms of the phenomena of womb-envy, exemplified by the biblical passage where God takes a rib from Adam to “create” Eve – an obvious reversal of the natural order of things, reflecting the inherent impotence men feel knowing their creative potency is secondary importance. It has been said, rightly, that the most powerful thing in the universe is to create life (is this not why we attribute this to “God”), and the second most powerful thing to take it. It is no coincidence that history, since it’s inception as recorded, is largely a documentation of the history of wars, of men “creating meaning” by killing men, and establishing symbol systems intended to capture by proxy the creative power latent within every woman’s body and experience.  And so, 10,000 years later, the world ruled by monotheistic, male-principled religious and cultural systems, both in secular and religious form, it seems that the facts of our biology are now intervening to shake up these largely subconscious belief systems in favor of an ancient truth: women are superior to men, fundamentally. (Though it is not a type of superiority to be used against the “weaker sex”: men, rather but to denote a higher responsibility, and perhaps greater need to be supported by men to get the job done, together, as inscribed in the natural order of things and its inherent design.)


The birth process, also, has been described as the closest thing to death without dying (it is ironic that anesthesiology, which could also be described in the same way, makes obstetrical interventions like C-section and epidural possible, at the same moment that it negates the spiritual experience of natural birth/women’s empowerment we are describing), offering women a window into the ‘in between’ and a direct experience of Source that men, less likely to experience it naturally would later emulate and access through the various technologies of shamanism.


Clearly, protecting the microbiome is of utmost importance if we are making the health of our future generations a priority. Indeed, ensuring the health of our offspring is perhaps the most fundamental evolutionary imperative we have.  How do we accomplish this? What is the microbiome but ultimately a selective array of commensal microorganisms that ultimately originated from the environment: in the air we breath, the soil we interact with, and the water and food, of course, we ingest. This means we can’t simply live in a hermetically sealed bubble of shopping for organic, non-GMO certified foods at Whole Foods, while the entire planet continues to go to post-industrial hell in a hand basket.  Our responsibility becomes distributed across everything in the world, and every impactful choice then becomes relevant to the fundamental issue and imperative at hand. With the microbial biodiversity in Big Ag, GM-based agricultural zones fire-bombed with biocides, by the very same corporations that either own or distribute the “organic brands” we all love to think will save our bodies, if not the planet, we need to step deeper into our activism by stepping out of the diversions and palliative measures that don’t result in lasting change.


When we work with the natural world, when we honor and acknowledge what is unknown about the complex web that we all share, we will bring back a vital health that now seems so far out of reach. When we engage technologies positioned in the war against germs and organisms, however, we are doomed to fail and to cripple not only our species but our home.


© November 9, 2017 GreenMedInfo LLC. This work is reproduced and distributed with the permission of GreenMedInfo LLC. Want to learn more from GreenMedInfo? Sign up for the newsletter here http://www.greenmedinfo.com/greenmed/newsletter.


The post How The Microbiome Destroyed The Ego, Vaccine Policy, And Patriarchy appeared first on The Sleuth Journal.

How The Microbiome Destroyed The Ego, Vaccine Policy, And Patriarchy

How The Microbiome Destroyed The Ego, Vaccine Policy, And Patriarchy | microbiome_revolutionary_implications1 | General Health Medical & Health Science & Technology Special Interests Vaccines


The relatively recent discovery of the microbiome is not only completely redefining what it means to be human, to have a body, to live on this earth, but is overturning belief systems and institutions that have enjoyed global penetrance for centuries.


A paradigm shift has occurred, so immense in implication, that the entire frame of reference for our species’ self-definition, as well as how we relate fundamentally to concepts like “germs,” have been transformed beyond recognition. This shift is underway and yet, despite popular interest in our gut ecology, the true implications remain unacknowledged.


It started with the discovery of the microbiome, a deceptively diminutive term, referring to an unfathomably complex array of microscopic microorganisms together weighing only 3-4 lbs. in the average human, represents a Copernican revolution when it comes to forming the new center, genetically and epigenetically, of what it means in biological terms to be human.


Considering the sheer density of genetic information contained within these commensals, as well as their immense contribution towards sustaining basic functions like digestion, immunity, and brain function, the “microbiome” could just as well be relabeled the “macrobiome”; that is, if we are focusing on the size of its importance rather than physical dimensionality.


For instance, if you take away the trillions of viruses, bacteria and fungi that coexist with our human cells (the so-called holobiont), only 1% of the genetic material that keeps us ticking, and has for hundreds of millions of years, remains. One percent isn’t that much for the ego to work with, especially considering it now has to thank what were formerly believed to be mostly “infectious agents” for the fact that it exists. Even more perplexing, the remaining 1% of our contributed DNA to the collective gene pool of the holobiont is at least 8% retroviral (yes, the same category as HIV) in origin!


Us Against Them?


Once the object of modern medicine’s fundamental responsibility – the human body – is redefined and/or perceived with greater veracity, and “germs” become less other and more self, a challenge for germ theory which seeks to differentiate between the “good” germs we are versus the “bad” ones out there that we must fight with antibiotics and vaccines.


As many readers are already poignantly aware, today’s political climate and agenda is unilaterally pro-vaccination on both sides of the aisle (conveniently funded by the same industry lobbyists), with a tidal wave of bills across the U.S. set to eliminate exemptions against mandatory vaccination. The rationale, of course, is that deadly germs can only be prevented from killing the presumably germ-free host through injecting dead, weakened or genetically modified germ components to “prevent” theoretical future exposures and infection. This concept is of course intellectually infantile, and if you do some investigating you’ll find it was never quite grounded in compelling evidence or science.


But the intellectual implications of the microbiome go even deeper than undermining germ theory, vaccine policy, and the culture of medical monotheism that upholds these constructs…


Maternal Origins of Health and Ultimately our Species Identity


Deep within the substratum of humanity’s largely unquestioned assumptions of what it means to be human, the microbiome has also fundamentally displaced a latent patriarchal prejudice concerning the relative importance and contribution of the man and woman towards the health and ultimately the continuation of our species.


It has been known for some time that only women pass down mitochondrial DNA, already tipping the scales in favor of her dominant position in contributing genetic information (the seat of our humanity or species identity, no?) to offspring. The microbiome, however, changes everything in favor of amplifying this asymmetry of hereditary influence. Since we are all designed to gestate in the womb and come through the birth canal, and since the neonate’s microbiome is therein derived and established thereof, it follows that most of our genetic information as holobionts is maternal in origin. Even when the original colonization eventually changes and is displaced through environmentally-acquired microbial strains as the infant, child, adolescent, and then adult, develops, the original terrain and subsequent trajectory of changes was established through the mother (unless of course we were C-sectioned into the world).


Put in simpler terms: if 99% of what it means to be human is microbiome-based, and if the mother contributes most, if not all, of the original starting material, or at least the baseline and trajectory of future changes in the inner terrain, then her contribution becomes vastly more important than that of the father.


Moreover, the conditions surrounding gestation (important because of maternal-to-fetal microbiome trafficking in utero), her general health, and the way in which she gives birth (home, birth center, or hospital) now take on vastly greater importance than previously imagined. In other words, being born in a hospital via C-section and vaccination, will produce, genetically and epigenetically, a human that is so different – qualitatively – from one born at home, naturally, that they could almost be classified as different species, despite sharing nearly identical eukaryotic DNA (remember, only 1% of the holobiont’s total).


Given this perspective, obstetric interventions are the archetypal expression of a male-dominated paradigm that seeks to manage a woman’s birth experience with largely unacknowledged consequences for the health of our species. Protecting health and preventing disease has now been traced back to the origins of the microbiome, best expressed through natural birth in the home, which has been estimated to be as much as 1,000 times safer than a hospital birth despite propaganda to the contrary.


In light of the new, microbiome-based view, the male role in protecting the health of women and children will be irrevocably downgraded in importance, not just professionally and medically, but biologically.  First, it is interesting to look at the ancient roots of the biology-based psychospiritual disparities that exist between men and women, and which still influence today’s practice of medicine.


It would appear that men have from the beginning of time envied the creative role of women in conception, pregnancy, birth and caretaking. Erich Fromm also described the pyschospiritual implications for men of this biologically-based existential disparity in terms of the phenomena of womb-envy, exemplified by the biblical passage where God takes a rib from Adam to “create” Eve – an obvious reversal of the natural order of things, reflecting the inherent impotence men feel knowing their creative potency is secondary importance. It has been said, rightly, that the most powerful thing in the universe is to create life (is this not why we attribute this to “God”), and the second most powerful thing to take it. It is no coincidence that history, since it’s inception as recorded, is largely a documentation of the history of wars, of men “creating meaning” by killing men, and establishing symbol systems intended to capture by proxy the creative power latent within every woman’s body and experience.  And so, 10,000 years later, the world ruled by monotheistic, male-principled religious and cultural systems, both in secular and religious form, it seems that the facts of our biology are now intervening to shake up these largely subconscious belief systems in favor of an ancient truth: women are superior to men, fundamentally. (Though it is not a type of superiority to be used against the “weaker sex”: men, rather but to denote a higher responsibility, and perhaps greater need to be supported by men to get the job done, together, as inscribed in the natural order of things and its inherent design.)


The birth process, also, has been described as the closest thing to death without dying (it is ironic that anesthesiology, which could also be described in the same way, makes obstetrical interventions like C-section and epidural possible, at the same moment that it negates the spiritual experience of natural birth/women’s empowerment we are describing), offering women a window into the ‘in between’ and a direct experience of Source that men, less likely to experience it naturally would later emulate and access through the various technologies of shamanism.


Clearly, protecting the microbiome is of utmost importance if we are making the health of our future generations a priority. Indeed, ensuring the health of our offspring is perhaps the most fundamental evolutionary imperative we have.  How do we accomplish this? What is the microbiome but ultimately a selective array of commensal microorganisms that ultimately originated from the environment: in the air we breath, the soil we interact with, and the water and food, of course, we ingest. This means we can’t simply live in a hermetically sealed bubble of shopping for organic, non-GMO certified foods at Whole Foods, while the entire planet continues to go to post-industrial hell in a hand basket.  Our responsibility becomes distributed across everything in the world, and every impactful choice then becomes relevant to the fundamental issue and imperative at hand. With the microbial biodiversity in Big Ag, GM-based agricultural zones fire-bombed with biocides, by the very same corporations that either own or distribute the “organic brands” we all love to think will save our bodies, if not the planet, we need to step deeper into our activism by stepping out of the diversions and palliative measures that don’t result in lasting change.


When we work with the natural world, when we honor and acknowledge what is unknown about the complex web that we all share, we will bring back a vital health that now seems so far out of reach. When we engage technologies positioned in the war against germs and organisms, however, we are doomed to fail and to cripple not only our species but our home.


© November 9, 2017 GreenMedInfo LLC. This work is reproduced and distributed with the permission of GreenMedInfo LLC. Want to learn more from GreenMedInfo? Sign up for the newsletter here http://www.greenmedinfo.com/greenmed/newsletter.


The post How The Microbiome Destroyed The Ego, Vaccine Policy, And Patriarchy appeared first on The Sleuth Journal.

Tuesday, June 13, 2017

Overuse of Antibiotics Linked to Precancerous Colon Polyps

Taking antibiotics for an extended period of time in early and middle adulthood may increase your risk of developing precancerous growths called polyps in your colon, a large study suggests. [1]


The research, published in the journal Gutadds to a growing collection of evidence that the type and diversity of gut microbes may play a significant role in the development of cancer.


Many people develop diarrhea when they take antibiotics. This is because the drug kills some of the normal gut bacteria, thus allowing an overgrowth of abnormal bacteria to dominate.




Read: Gut Health is Directly Linked to Chronic Illness, Overall Health


For the study, researchers in the U.S. tracked the health of over 120,000 nurses between the ages of 30 and 55 who took part in the Nurses Health Study that launched in 1976. The team found that between 2004 and 2010, 1,194 nurses were diagnosed with abnormal growths in the colon and rectum.


Participants who had taken antibiotics for two months or more between the ages of 20 and 39 were 36% more likely to be diagnosed with a polyp, called an adenoma, compared with those who hadn’t taken a prolonged course of antibiotics during their 20s and 30s.


Women who had taken antibiotics for two months or more during their 40’s or 50’s were 69% more likely to be diagnosed with a polyp.


Similarly, women who took antibiotics for 15 days or more between ages 20 and 39, and between ages 40 and 59, were 73% more likely to be diagnosed with an adenoma.


Source: Your Health Blog

Read: Why Probiotics are Essential if You are Taking Antibiotics


Associate Professor Graham Newstead, the head of the colorectal unit at the Prince of Wales private hospital and director of Bowel Cancer Australia, said:


“It does seem to indicate that people who have too many antibiotics might be at more risk of [sic] getting polyps than people who have less of them.


And, remembering that not all polyps turn to cancer but the cancer comes from the polyps. If you have more polyps or tendency to get polyps then maybe you are slightly more at risk of getting cancer.” [1]


The researchers wrote in the report:


“Antibiotics fundamentally alter the gut microbiome, by curbing the diversity and number of bacteria, and reducing the resistance to hostile bugs.


This might all have a crucial role in the development of bowel cancer, added to which the bugs that require antibiotics may induce inflammation, which is a known risk for the development of bowel cancer.


The findings if confirmed by other studies, suggest the potential need to limit the use of antibiotics and sources of inflammation that may drive tumor formation.” [2]


Other Risk Factors for Colorectal Cancer


Occurrence of polyps in the gastrointestinal tract.

Dr. Andrew Chan, an associate professor of medicine at Harvard Medical School, said the study doesn’t prove that antibiotics cause polyps, only that there is a connection. [3]


And while the study looked at women, Chan said the study likely also holds true for men.




“More research needs to be done to understand the interaction between alterations in one’s gut bacteria and future risk of colorectal cancer.” [3]


There are several known risk factors for bowel cancer besides polyps, including:


  • Being overweight or obese

  • Not getting enough physical activity

  • Diets that are high in red meat and processed meats

  • Cooking meats at very high temperatures (frying, boiling, or grilling)

  • Smoking

  • Heavy alcohol use

  • Being age 50 or older

  • A personal history of colorectal cancer

  • A personal history of inflammatory bowel disease

  • A family history of colorectal cancer or polyps

  • Certain inherited syndromes

  • Being African-American or a Jew of Eastern European descent

  • Having type 2 diabetes [4]

There is even some research that suggests that working a night shift regularly may increase your risk for colorectal cancer, possibly due to changes in levels of melatonin.


Sources:


[1] The Guardian


[2] BBC News


[3] WebMD


[4] American Cancer Society


Your Health Blog



Storable Food


About Julie Fidler:


Author Image
Julie Fidler is a freelance writer, legal blogger, and the author of Adventures in Holy Matrimony: For Better or the Absolute Worst. She lives in Pennsylvania with her husband and two ridiculously spoiled cats. She occasionally pontificates on her blog.

Tuesday, May 23, 2017

Could “Advanced Probiotics” Soon Treat Parkinson’s Disease?

Researchers say they’ve uncovered a link between gut bacteria and the onset of Parkinson’s disease. The findings suggest a new way of treating one of the world’s most debilitating diseases.



Parkinson’s causes a variety of physical changes, especially in the digestive system. Patients often complain of constipation or bloating, trouble swallowing, and indigestion. These symptoms often begin years before patients lose motor control, the hallmark of the disease. [1]




For the study, researchers worked with mouse models of the brain disorder and discovered that changes in gut microbes may play a role in triggering Parkinson’s. The team, led by Sarkis Mazmanian of the California Institute of Technology, transplanted fecal samples from people with Parkinson’s into mice raised in a germ-free setting and found that the rodents’ symptoms worsened. The same did not happen when the mice were injected with fecal matter from people without Parkinson’s.


Mazmanian says:


“What we extrapolate from that is that there is a microbial profile that is different in Parkinson’s. Perhaps those changes are contributing to disease; we’re a long way from proving that’s the case in humans, but at least in mouse models that’s what the data suggest.”


Mazmanian theorizes that breakdown products of the bacteria are toxic and circulate to the brain. There are also many nerve connections between the intestines and the brain, so it’s possible that influencing the nerves in the gut affects nerves in the brain. [2]


Source: Detroit Free Press

The researchers wrote in the journal Cell:


“Coupled with emerging research that has linked gut bacteria to disorders such as anxiety, depression, and autism, we propose the provocative hypothesis that certain neurologic conditions that have classically been studied as disorders of the brain may also have etiologies in the gut.”


Related: Autistic Children Found to Have Fewer Healthy Gut Bacteria


There are about a dozen species of microbes that might be important to the disease, according to Mazmanian, and some of them are missing in people with Parkinson’s disease. This suggests the missing microbes may provide some protection against the neurodegenerative disorder. [1]


Mazmanian says:


“There are particular classes of bacteria that are selectively missing or depleted in the Parkinson’s population and found in the healthy population.” [2]


The study doesn’t show that gut microbes cause Parkinson’s, but it suggests that a pivot from treating the brain to treating the gut might be more effective. The researchers hope the findings will lead to the development of “next generation” probiotics that are like commercially available probiotics on steroids. [3]


Mazmanian says:


“One can imagine one day, maybe in our lifetimes, patients will be prescribed drugs, and in the pills will be the bacteria that protect them from disease or even maybe treat their disease symptoms.”





Sources:


[1] Time


[2] NBC News


Detroit Free Press



Storable Food


About Julie Fidler:


Author Image
Julie Fidler is a freelance writer, legal blogger, and the author of Adventures in Holy Matrimony: For Better or the Absolute Worst. She lives in Pennsylvania with her husband and two ridiculously spoiled cats. She occasionally pontificates on her blog.