Showing posts with label lung cancer. Show all posts
Showing posts with label lung cancer. Show all posts

Wednesday, August 9, 2017

Study Links Diets High in Saturated Fat to Lung Cancer

Researchers point out a correlation between saturated fat consumption and lung cancer, suggesting that people who eat a diet high in saturated fat (found in butter and beef) have a greater risk of developing lung cancer than those who eat a low-fat diet. Smoking increases the risk even further. [1]


Researchers found that study participants who ate the most total fat and saturated fat were 14% more likely to go on to have the disease, compared to those who limited their fat consumption. The risk also increased 15% among current and former smokers, the study found.


Study co-author Danxia Yu, of Vanderbilt University Medical Center, said the very best way to prevent lung cancer is to simply not smoke, but added that eating a healthy diet most likely lowers the risk, too.



She said:



“Specifically, our findings suggest that increasing polyunsaturated fat intake while reducing saturated fat intake, especially among smokers and recent quitters, may (help prevent) not only cardiovascular disease but also lung cancer.”



According to the American Heart Association (AHA), people can help prevent cardiovascular disease by eating either a Mediterranean-style diet, or the Dietary Approaches to Stop Hypertension (DASH) diet. Both types of eating patterns emphasize cooking with vegetable oils containing unsaturated fats, and copious amounts of fresh fruits, vegetables, whole grains, fish, and poultry.


Both diets encourage limiting red meats, added sugars, and salt. There is, however, evidence to suggest that high-fat healthy oils such as olive oil are safe to consume as part of a Mediterranean-style diet.


For the study, published July 25, 2017 in the Journal of Clinical Oncology, researchers looked at data on 1,445,850 participants from a pooled analysis of 10 prospective cohort studies from the U.S., Europe, and Asia. [2]


The authors wrote:



“Modifying dietary fat intake (i.e., replacing saturated fat with polyunsaturated fat) may reduce lung cancer risk, particularly among smokers and for squamous cell and small cell carcinoma.”



In fact, substituting 5% of calories from saturated fat with unsaturated fat was linked with a 16% lower risk of small cell lung cancer, and 17% lower odds of squamous cell carcinoma. [1]


However, the study was limited in 3 ways.


  • First, participants’ dietary information was only gathered at one point, leaving researchers unable to track how altering eating habits might affect the odds of developing cancer.

  • Second, the study did not account for sugar and trans fats, both known to fuel cancer.

  • Then there’s this: Ursula Schwab of the Institute of Public Health and Clinical Nutrition at the University of Eastern Finland in Kuopio, who wasn’t involved in the study, says it’s possible that other poor eating habits, not fat, help increase the risk of lung cancer.


“We need antioxidants, vitamins and minerals, as well as unsaturated fatty acids. A typical Western diet has a low content of these essential nutrients and a high content of saturated fat.”



Based on the information provided, it seems that the correlation between saturated fat consumption and lung cancer is weak and far from conclusive.


Sources:


[1] Reuters


[2] HealthDay News



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About Julie Fidler:
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Julie Fidler is a freelance writer, legal blogger, and the author of Adventures in Holy Matrimony: For Better or the Absolute Worst. She lives in Pennsylvania with her husband and two ridiculously spoiled cats. She occasionally pontificates on her blog.

This Chemotherapy Drug May Help Breast Cancer SPREAD

An anticancer drug known as paclitaxel may actually cause breast cancer to spread to the lungs, according to the rather horrifying results of a recent study.


Earlier in 2017, a study revealed that chemotherapy may cause cellular changes in both a breast cancer mouse model and in a small number of human breast cancer sufferers.


Tsonwin Hai, a professor of biological chemistry and pharmacology, and a team of colleagues have built on this research by studying the effects of the chemotherapy drug on the spread of breast cancer cells to the lungs.



Paclitaxel is one of the first lines of defense for several types of cancer, including ovarian, breast, and lung cancer.


In the recent study, Hai and her team evaluated a rodent model as well as data from breast cancer patients to determine the ways in which paclitaxel may enable breast cancer to metastasize (spread from one part of the body to another).


The scientists found that in those who underwent chemotherapy, a gene called Atf3 – which is activated by stress – is over-expressed compared with individuals who did not receive the treatment.


Hai said:



“This gene seems to do two things at once: essentially help distribute the ‘seeds’ (cancer cells) and fertilize the ‘soil’ (the lung).”



Signals sent by the chemotherapy increase the number of “molecular doors,” or openings, which allow cancer cells to escape from the main tumor into the bloodstream, where the cells are then free to travel to other organs. [2]


Hai explained:



“I think it’s an active process—a biological change in which the cancer cells are beckoned to escape into the blood—rather than a passive process in which the cancer cells get into the bloodstream because of leaky vessels.”



Likewise, paclitaxel appears to create a chain of events that makes the lung tissue a potentially fertile breeding ground for circulating cancer cells to take hold and spread.


Said Hai:



“There are signals that help cancer cells enter the lungs and set up shop, that make the environment more immunologically tolerant to cancer cells.


At this point, what our study and the recent literature on chemotherapy taught us is that it is prudent to keep our mind open, realizing that chemo can help treat cancer, but at the same time may increase the possibility of the spread of that cancer.”



More research is needed to learn whether or not the findings in rodents also apply to human cancer patients. Breast cancer cells tend to be more aggressive in mice.


She concluded:



“That chemotherapy can paradoxically promote cancer progression is an emerging revelation in cancer research. However, a molecular-level understanding of this devastating effect is not clear.”




Of course, there have been other studies that have suggested that chemotherapy either makes cancer worse, or spreads it to other locations in the body.


A 2016 study by Public Health England and Cancer Research UK found that, across England, 8.4% of patients with lung cancer and 2.4% of breast cancer patients died within a month of starting chemo, suggesting that the treatment itself is what killed them. The percentage of cancer patients who died within a month of starting the treatment was much higher than that at some hospitals. [3]


Cancer is an evil beast, and no one with cancer should ever be shamed or ridiculed for the treatment they choose. But in light of the growing body of evidence that chemotherapy and other anticancer drugs often do more harm than good, doctors would be wise to encourage patients to at least investigate other treatments.


Sources:


[1] Medical News Today


[2] Medical Xpress


[3] The Telegraph



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About Julie Fidler:
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Julie Fidler is a freelance writer, legal blogger, and the author of Adventures in Holy Matrimony: For Better or the Absolute Worst. She lives in Pennsylvania with her husband and two ridiculously spoiled cats. She occasionally pontificates on her blog.

Wednesday, June 28, 2017

China Now Home to the World’s Largest Floating Solar Plant

In the beginning of June 2017, workers brought a solar energy plant online capable of producing 40 megawatts of power. That’s cool all by itself, but this solar “farm” floats on a manmade lake in China’s Anhui province, and it is the largest floating solar project in the world. [1]


The massive power plant was built by Sungrow Power Supply, and can produce enough energy to power 15,000 homes. The exact size of the operation has not been revealed, but it produces twice as much energy as the previous holder of the largest-floating-solar-plant title, which was launched by Xinyi Solar in 2016.


Building solar plants on bodies of water helps prevent agricultural land and terrestrial ecosystems from being developed for energy use – especially manmade lakes that are not ecologically sensitive. The water cools the electronics in the solar panels, which helps them work more efficiently.




Britain did the same thing for similar reasons in 2016 when it built a 23,000-panel floating solar farm on the Queen Elizabeth II reservoir near Heathrow Airport. The plant helps power the Thames Water treatment plant. The solar farm in Anhui province consists of 160,000 solar panels.


China is beginning to lead the world in clean energy investment, and the nation is projected to get 20% of its power consumption from low-emission energy by 2030. [2]


China Still Stricken by Toxic Air


China is plagued by toxic air pollution – smog is such a problem that the country expects to have more than 800,000 cases of lung cancer a year by 2020. The city of Beijing is currently the world’s top carbon emitter, with 2/3 of its electricity still fueled by coal. [3]


Source: Yale Center for Environmental Law & Policy

But the country has been working on innovative ways of fighting pollution. In 2018, Nanjing, China, is expected to start building Nanjing Green Towers, 2 buildings that will serve as vertical forests stylized with about 1,100 trees and more than 2,500 various shrubs and plants. The towers will absorb enough carbon dioxide to create 132 pounds of oxygen daily.


Though China’s floating solar energy plant is the largest of its type in the world, it pales in comparison to the land-locked Longyangxia Dam Solar Park, which hosts 4 million solar panels – together producing 850 megawatts of energy. And that project will eventually pale in comparison to a project in the Ningxia Autonomous Region, which will house more than 6 million solar panels and produce 2 gigawatts of power.


Sources:


[1] Smithsonian.com


[2] Mother Nature Network


[3] Phys.org


Yale Center for Environmental Law & Policy



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About Julie Fidler:


Author Image
Julie Fidler is a freelance writer, legal blogger, and the author of Adventures in Holy Matrimony: For Better or the Absolute Worst. She lives in Pennsylvania with her husband and two ridiculously spoiled cats. She occasionally pontificates on her blog.