Showing posts with label heartburn. Show all posts
Showing posts with label heartburn. Show all posts

Sunday, August 20, 2017

Shocking Information About Acid Reflux

Shocking Information About Acid Reflux | Acid-Reflux | General Health Special Interests


You probably hear a lot about acid reflux, or perhaps you suffer from it yourself. But what exactly is acid reflux? Well, right at your stomach opening is a valve called the lower esophageal sphincter (LES). Normally, the LES opens and closes as it’s supposed to, but sometimes it messes up. When that happens, your stomach acid can occasionally escape and flow backwards—that is, up into your esophagus—and if you’ve ever experienced reflux, you know you’re left with some pretty uncomfortable feelings. Not only is it acutely painful, but it can lead to serious health consequences.


Facts about Acid Reflux


Many over-the-counter medications on the market work to fight acid reflux after it starts, and it usually works. The issue with these drugs, however, is that they’re only treating symptoms of the disorder. Regardless of how much you use, symptoms usually flare back up, leading to an endless cycle of drug dependency. Even the commercials for these medications make it look like you can eat whatever you want as long as you have drugs in-hand.


Let’s look at the 4 most shocking facts about acid reflux:



1. Spicy Food Doesn’t Trigger Acid Reflux


All that spicy food you thought led to acid reflux? Well it turns out that might not be the trigger at all. A recent study from the director of Stanford’s Esophageal and Small Bowel Disorder Center suggests that only an unlucky few will actually have reflux triggered by certain foods. [1]


2. Acid Reflux Ruins Sleep and Causes Sleep Apnea


If you’ve ever tried to sleep with reflux symptoms, this might seem like a no-brainer, but there’s recent evidence suggesting acid reflux can significantly affect quality of sleep. The same research also suggests it could cause an even serious disorder like sleep apnea. [2][3] Not only that, but the widespread effects can take their toll on overall quality of life—leading to loss of work productivity and increased economic burdens. [4]


3. Acid Reflux Often Coexists with IBS


Recent research suggests those with Irritable Bowel Syndrome (IBS) are also very likely to have acid reflux. [5] While both are fairly common gastrointestinal issues, the main view in clinical practice was that these two issues had no link. A study published in the World Journal of Gastroenterology, however, suggests that the two are “actually parts of the same spectrum of diseases.”


4. Acid Reflux May Lead to Cancer


Some studies suggest acid reflux is connected to a higher chance of developing esophageal cancer. [6] While the exact link is still unknown, any increased risk for cancer is bad news. Another study suggests, though, that the risk could come from the reflux of stomach acid itself, and that the more reflux you experience and the longer you have it, the higher your risk for certain conditions. [7]


Something to Think About


But before you reach for your old standby remedy, all those conventional treatments can have some pretty serious side effects, including bacterial infections, fractures in postmenopausal women, and heart disease. [8][9][10] There’s an easy natural remedy though. Taking probiotics, to start, is always a smart option for all ages; it’s thought to be particularly effective in newborns to help reduce gastrointestinal symptoms. [11]


How do you deal with acid reflux? Tell us in the comments.


References:


1. Kaltenbach, T. et al. Are lifestyle measures effective in patients with gastroesophageal reflux disease? An evidence-based approach. Archives of Internal Medicine. 166 (9).


2. Lacy, B. et al. Functional Dyspepsia Is Associated With Sleep Disorders. Clinical Gastroenterology and Hepatology. 9 (5).


3. American College of Gastroenterology. ‘Silent’ Nighttime Acid Reflux Symptoms Can Cause Poor Sleep And Sleep Apnea. ScienceDaily.


4. Mody, R. et al. Effects of Gastroesophageal Reflux Disease on Sleep and Outcomes. Clinical Gastroenterology and Hepatology. 7 (9).


5. Yarandi, S. S. et al. Overlapping gastroesophageal reflux disease and irritable bowel syndrome: Increased dysfunctional symptoms. World Journal of Gastroenterology. 16 (10).


6. Mayo Clinic. Mayo Clinic Studies Find Association Between Acid Reflux And Esophageal Cancer. ScienceDaily.


7. Souza, R. Acid, Bile, and CDX: the ABCs of making Barrett’s metaplasia. American Journal of Physiology: Gastrointestinal and Liver Physiology. 295 (2).


8. Gray, S. L. et al. Proton Pump Inhibitor Use, Hip Fracture, and Change in Bone Mineral Density in Postmenopausal Women: Results From the Women’s Health Initiative. JAMA Internal Medicine. 170 (9).


9. Linsky, A. et al. Proton Pump Inhibitors and Risk for Recurrent Clostridium difficile Infection. JAMA Internal Medicine. 170 (9).


10. Ghebremariam, Y. T. et al. An Unexpected Effect of Proton Pump Inhibitors: Elevation of the Cardiovascular Risk Factor ADMA. Circulation. 128.


11. Indrio, F. et al. Prophylactic Use of a Probiotic in the Prevention of Colic, Regurgitation, and Functional Constipation. JAMA Pediatrics. 168 (3).

Saturday, August 19, 2017

Heartburn Drugs Linked to up to 94% Increased Risk of Ischemic Stroke

Ads for heartburn medication are everywhere, with media being littered with ads for “the big guns” like Prilosec, Nexium, Prevacid, and Protonix. They must be safe, right? Well, it’s still important to know the risks – as one study shows that people who take proton pump inhibitors (PPI’s) have a higher risk of stroke.


Lead study author Dr. Thomas Sehested says that, overall, taking PPI’s increase your stroke risk by 21%. [1]


What are PPI’s?


This popular class of drugs works by reducing the amount of acid produced in the stomach, which cuts the amount of stomach acid that backs up into the esophagus, producing that all-too-familiar burning sensation.



Everyone has heartburn from time to time, but a person who experiences heartburn twice a week may have a condition called gastroesophageal reflux disease, or GERD. Over time, if GERD is not treated, it can cause serious illness and injury to the esophagus, including ulcers, scarring, and even cancer.


These drugs are supposed to help with that.



Mapping the PPI-Stroke Link


In the study, Sehested and colleagues analyzed data from 244,679 adults from Denmark (average age 57) who underwent endoscopy to determine the cause of their stomach pain or indigestion.


During the average of 6 years of follow-up, 9,489 patients experienced a first-time ischemic stroke.


The researchers looked at the patients’ use of 1 of 4 PPI’s – omeprazole (Prilosec), pantoprazole (Protonix), lansoprazole (Prevacid), and esomeprazole (Nexium) – to see if use of the medications was associated with ischemic stroke risk, which occurs when a blood clot blocks the flow of blood to the brain.



Overall, the researchers found that individuals were at 21% greater risk of ischemic stroke when they were using PPI’s compared to when they were not using the drugs.


The team found that there was little or no greater risk of stroke with low doses of PPI’s. What’s more, another group of medications used to treat heartburn – called H2 blockers – were not linked to increased stroke risk.


People taking lansoprazole (Prevacid) had the greatest increased risk of ischemic stroke – 94%. Lansoprazole (Prevacid) fared the best, increasing the risk of ischemic stroke 30%. [2]


In previous studies, PPI use has been associated with heart disease, heart attacks, and dementia. [1]


Cause-and-Effect Not Proven


Because the study was observational, the researchers could not prove cause and effect between PPI use and increased stroke risk. However, the increased risk remained after the team accounted for possible confounding factors, including age, gender, high blood pressure, atrial fibrillation, and use of medications that have been linked to poorer cardiovascular health.


The scientists said that people should be cautious about taking PPI medications, which are now available over the counter.


Sehested said that doctors, too, should be cautious when deciding to prescribe PPI medications to patients, and for how long. He added:



“We know that from prior studies that a lot of individuals are using PPIs for a much longer time than indicated, which is especially true for elderly patients.”




Sehested said it’s not clear why PPI’s may be harmful to cardiovascular health. He did point out that the medications might reduce levels of biochemicals which are vital to the maintenance of blood vessels. A lack of these biochemicals in the body could cause hardening of the arteries. [2]


PPI’s have also been linked to increased risks of bone fractures and malabsorption, as well as Clostridum difficile (C. diff), a bacteria known to cause severe, sometimes fatal, diarrhea and inflammation of the colon.


Source: SteadyHealth

If you’re a heartburn sufferer, there are natural ways to get rid of your pain. A 2007 study in Molecular Research and Food Nutrition, researchers found that ginger got rid of heartburn 8 times better than Prevacid. Other people have had success with drinking apple cider vinegar, or consuming a mixture of 1/4 teaspoon of baking soda dissolved in 4 ounces of water.


Sources:


[1] Medical News Today


[2] Chicago Tribune


Steady Health



Storable Food





About Julie Fidler:
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Julie Fidler is a freelance writer, legal blogger, and the author of Adventures in Holy Matrimony: For Better or the Absolute Worst. She lives in Pennsylvania with her husband and two ridiculously spoiled cats. She occasionally pontificates on her blog.